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Article

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.

Life sciences - 1 Aug 2011

Jiang Rongrong, Yamaori Satoshi, Takeda Shuso, Yamamoto Ikuo, Watanabe Kazuhito

Abstract excerpt

AIMS: Cannabidiol (CBD), one of the major constituents in marijuana, has been shown to be extensively metabolized by experimental animals and humans. However, human hepatic enzymes responsible for the CBD metabolism remain to be elucidated. In this study, we examined in vitro metabolism of CBD with human liver microsomes (HLMs) to clarify cytochrome P450 (CYP) isoforms involved in the CBD oxidations. MAIN...

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Source

Identifiers

PMID: 21704641
DOI: 10.1016/j.lfs.2011.05.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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