Article
Molecular structures of two human DNA topoisomerase I retrosequences.
Gene - 16 Jul 1990
Yang G C, Kunze N, Baumgärtner B, Jiang Z Y, Sapp M, Knippers R, Richter A
Abstract excerpt
We have isolated recombinant lambda-phage clones that contain sequences complementary to the 3' half of the cDNA encoding human topoisomerase I (hTOP1). These lambda clones belong to three distinct classes: class-I clones contain sequences from the active gene located on human chromosome 20. Class-II and class-III clones contain sequences corresponding to the cDNA encoding hTOP1 from nucleotide (nt) 2208 to 3434...
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