Article
Molecular structures of two human DNA topoisomerase I retrosequences.
Gene - 16 Jul 1990
Yang G C, Kunze N, Baumgärtner B, Jiang Z Y, Sapp M, Knippers R, Richter A
Abstract excerpt
We have isolated recombinant lambda-phage clones that contain sequences complementary to the 3' half of the cDNA encoding human topoisomerase I (hTOP1). These lambda clones belong to three distinct classes: class-I clones contain sequences from the active gene located on human chromosome 20. Clas...
Topics
- Base Sequence
- Chromosomes, Human, Pair 1
- Cloning, Molecular
- Codon
- DNA Topoisomerases, Type I
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Pseudogenes
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping
