Article
Different CHEK2 germline mutations are associated with distinct immunophenotypic molecular subtypes of breast cancer.
Breast cancer research and treatment - 1 Apr 2012
Domagala Pawel, Wokolorczyk Dominika, Cybulski Cezary, Huzarski Tomasz, Lubinski Jan, Domagala Wenancjusz
Abstract excerpt
Germline mutations in BRCA1 were already linked to basal-like subtype of immunophenotypic molecular classification of breast cancer (BC). However, it is not known whether mutations in other BC susceptibility genes are associated with molecular subtypes of this cancer. We tested the hypothesis that distinct mutations in another BC susceptibility gene involved in DNA repair, i.e., CHEK2 may be associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.