Article
Genome-wide association of BMI in African Americans.
Obesity (Silver Spring, Md.) - 1 Mar 2012
Ng Maggie C Y, Hester Jessica M, Wing Maria R, Li Jiang, Xu Jianzhao, Hicks Pamela J, Roh Bong H, Lu Lingyi, Divers Jasmin, Langefeld Carl D, Freedman Barry I, Palmer Nichole D, Bowden Donald W
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified multiple novel loci associated with obesity in Europeans but results in other ethnicities are less convincing. Here, we report a two-stage GWAS of BMI in African Americans. The GWAS was performed using the Affymetrix 6.0 platform in 816 nondiabetic and 899 diabetic nephropathy subjects. 746,626 single-nucleotide polymorphisms (SNPs) were tested for...
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