Article
Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate.
American journal of human genetics - 15 Jul 2011
Kullo Iftikhar J, Ding Keyue, Shameer Khader, McCarty Catherine A, Jarvik Gail P, Denny Joshua C, Ritchie Marylyn D, Ye Zi, Crosslin David R, Chisholm Rex L, Manolio Teri A, Chute Christopher G
Abstract excerpt
The erythrocyte sedimentation rate (ESR), a commonly performed test of the acute phase response, is the rate at which erythrocytes sediment in vitro in 1 hr. The molecular basis of erythrocyte sedimentation is unknown. To identify genetic variants associated with ESR, we carried out a genome-wide association study of 7607 patients in the Electronic Medical Records and Genomics (eMERGE) network. The discovery...
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