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Article

Complement Receptor 1 Gene Polymorphisms in Sarcoidosis

1 Jul 2002

Abstract excerpt

Sarcoidosis is likely to result from exposure of genetically susceptible hosts to environmental agents. Erythrocyte (E) complement receptor 1 (CR1) is a membrane protein mediating the transport of immune complexes (ICs) to phagocytes, and at least three polymorphisms on the CR1 gene are related to erythrocyte surface density of CR1 molecules, in turn related to the rate of IC clearance from circulation. We...

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PMID: 12091241
DOI: 10.1165/ajrcmb.27.1.4805

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