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Article

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

Nature - 12 Aug 2004

Chang Sarah, Johnston Robert J, Frøkjaer-Jensen Christian, Lockery Shawn, Hobert Oliver

Abstract excerpt

Animal microRNAs (miRNAs) are gene regulatory factors that prevent the expression of specific messenger RNA targets by binding to their 3' untranslated region. The Caenorhabditis elegans lsy-6 miRNA (for lateral symmetry defective) is required for the left/right asymmetric expression of guanyl cyclase (gcy) genes in two chemosensory neurons termed ASE left (ASEL) and ASE right (ASER). The asymmetric expression of...

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PMID: 15306811
DOI: 10.1038/nature02752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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