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Article

Genotyping HapSTR loci: phase determination from direct sequencing of PCR products.

Molecular ecology resources - 1 Nov 2011

Sorenson Michael D, DaCosta Jeffrey M

Abstract excerpt

HapSTRs combine information from a microsatellite (or simple tandem repeat, STR) with one or more single nucleotide polymorphisms in the DNA sequence immediately flanking the STR. These loci may offer increased power for the estimation of demographic parameters, but also present some challenges for data collection and analysis. We describe a process for inferring HapSTR alleles, including the flanking haplotypes,...

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PMID: 21692999
DOI: 10.1111/j.1755-0998.2011.03036.x

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