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Article

Varying coefficient model for gene-environment interaction: a non-linear look.

Bioinformatics (Oxford, England) - 1 Aug 2011

Ma Shujie, Yang Lijian, Romero Roberto, Cui Yuehua

Abstract excerpt

MOTIVATION: The genetic basis of complex traits often involves the function of multiple genetic factors, their interactions and the interaction between the genetic and environmental factors. Gene-environment (G×E) interaction is considered pivotal in determining trait variations and susceptibility of many genetic disorders such as neurodegenerative diseases or mental disorders. Regression-based methods assuming a...

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Identifiers

PMID: 21690105
DOI: 10.1093/bioinformatics/btr318
PMCID: PMC3137212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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