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Article

A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects.

Behavior genetics - 1 Jul 2023

Zhou Zhengyang, Ku Hung-Chih, Manning Sydney E, Zhang Ming, Xing Chao

Abstract excerpt

Most human traits are influenced by the interplay between genetic and environmental factors. Many statistical methods have been proposed to screen for gene-environment interaction (GxE) in the post genome-wide association study era. However, most of the existing methods assume a linear interaction between genetic and environmental factors toward phenotypic variations, which diminishes statistical power in the...

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Identifiers

PMID: 36622576
DOI: 10.1007/s10519-022-10131-w
PMCID: PMC10277225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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