Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells.

PloS one - 1 Jan 2011

Kumar Anupam, Gao Hui, Xu Jia, Reuben James, Yu Dihua, Mehta Kapil

Abstract excerpt

Cancer stem cells (CSCs) or tumor initiating cells (TICs) make up only a small fraction of total tumor cell population, but recent evidence suggests that they are responsible for tumor initiation and the maintenance of tumor growth. Whether CSCs/TICs originate from normal stem cells or result fro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD24 Antigen
Share to Cell Count
Share to GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyaluronan Receptors

Share to Mammary Glands, Human

Share to Neoplastic Stem Cells

Share to Protein Glutamine gamma Glutamyltransferase 2

Share to Transglutaminases

Source

Open in PubMed Open full text

Identifiers

PMID: 21687668
DOI: 10.1371/journal.pone.0020701
PMCID: PMC3110765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21687668-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells.PMID 21687668Read ↗

Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells.Semantic proximity Read ↗

Transglutaminase 2 Regulates Self-renewal and Stem Cell Marker of Human Colorectal Cancer Stem CellsSemantic proximity Read ↗

The transglutaminase 2 cancer cell survival factor maintains mTOR activity to drive an aggressive cancer phenotype.Semantic proximity Read ↗

Transglutaminase 2 Maintains Hepatocyte Growth Factor Signaling to Enhance the Cancer Cell Phenotype.Semantic proximity Read ↗

PTTG1 Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell PopulationSemantic proximity Read ↗

Tissue transglutaminase: a new target to reverse cancer drug resistanceSemantic proximity Read ↗

Transglutaminase 2 takes center stage as a cancer cell survival factor and therapy targetSemantic proximity Read ↗

Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells.Semantic proximity Read ↗

Loss of host tissue transglutaminase boosts antitumor T cell immunity by altering STAT1/STAT3 phosphorylation in ovarian cancerSemantic proximity Read ↗

Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype.Semantic proximity Read ↗

Clinical and biological significance of tissue transglutaminase in ovarian carcinoma.Semantic proximity Read ↗

Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.