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Article

Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells.

PloS one - 1 Jan 2011

Kumar Anupam, Gao Hui, Xu Jia, Reuben James, Yu Dihua, Mehta Kapil

Abstract excerpt

Cancer stem cells (CSCs) or tumor initiating cells (TICs) make up only a small fraction of total tumor cell population, but recent evidence suggests that they are responsible for tumor initiation and the maintenance of tumor growth. Whether CSCs/TICs originate from normal stem cells or result from the dedifferentiation of terminally differentiated cells remains unknown. Here we provide evidence that sustained...

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Source

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Identifiers

PMID: 21687668
DOI: 10.1371/journal.pone.0020701
PMCID: PMC3110765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells.PMID 21687668Read ↗

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