Article
NS3 protease of genotype 3 subtype h HCV identified in southeastern France.
Antiviral therapy - 1 Jan 2011
Colson Philippe, Gayet Stéphane, Gerolami René
Abstract excerpt
HCV displays considerable levels of nucleotide and amino acid diversity. Recently, the relevance of natural polymorphisms in worldwide isolates has been addressed in view of future protease inhibitor (PI)-based treatments; genotype- and subtype-specific natural polymorphisms within HCV NS3 protease were identified at amino acid sites associated either with resistance to PIs or with compensatory mutations. Here,...
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