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Induction of Autophagy Promotes Preattachment Development of Bovine Embryos by Reducing Endoplasmic Reticulum Stress1

27 Apr 2012

Abstract excerpt

The coupling of autophagy and endoplasmic reticulum (ER) stress has been implicated in a variety of biological processes; however, little is known regarding the involvement of the autophagy/ER stress pathway in early embryogenesis or the underlying mechanism(s). Here, we showed that the developmental competence of in vitro-produced (IVP) bovine embryos was highly dependent on the autophagy/ER stress balance....

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PMID: 22539678
DOI: 10.1095/biolreprod.111.097949

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