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The Role of Autophagy During Development in Higher Eukaryotes

12 Jul 2010

Abstract excerpt

Autophagy is a lysosome-mediated degradation pathway used by eukaryotes to recycle cytosolic components in both basal and stress conditions. Several genes have been described as regulators of autophagy, many of them being evolutionarily conserved from yeast to mammals. The study of autophagy-defective model systems has made it possible to highlight the importance of correctly functioning autophagic machinery in...

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PMID: 20633243
DOI: 10.1111/j.1600-0854.2010.01103.x

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