Article
Pretreatment prediction of anemia progression by pegylated interferon alpha-2b plus ribavirin combination therapy in chronic hepatitis C infection: decision-tree analysis.
Journal of gastroenterology - 1 Sept 2011
Hiramatsu Naoki, Kurosaki Masayuki, Sakamoto Naoya, Iwasaki Manabu, Sakamoto Minoru, Suzuki Yoshiyuki, Sugauchi Fuminaka, Tamori Akihiro, Kakinnuma Sei, Matsuura Kentaro, Izumi Namiki
Abstract excerpt
BACKGROUND: This study aimed to develop a model to predict the development of severe anemia during pegylated interferon alpha-2b plus ribavirin combination therapy. METHODS: Data were collected from 1081 genotype 1b chronic hepatitis C patients who were treated at 6 hospitals in Japan. These patients were randomly assigned to a model-building group (n = 691) or an internal validation group (n = 390). Factors...
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