Article
Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis.
Antiviral therapy - 1 Jan 2012
Kurosaki Masayuki, Hiramatsu Naoki, Sakamoto Minoru, Suzuki Yoshiyuki, Iwasaki Manabu, Tamori Akihiro, Matsuura Kentaro, Kakinuma Sei, Sugauchi Fuminaka, Sakamoto Naoya, Nakagawa Mina, Yatsuhashi Hiroshi, Izumi Namiki
Abstract excerpt
BACKGROUND: This study aimed to define factors associated with relapse among responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in chronic hepatitis C. METHODS: A cohort of genotype 1b chronic hepatitis C patients treated with PEG-IFN plus RBV and who had an undetectable HCV RNA by week 12 (n=951) were randomly assigned to model derivation (n=636) or internal validation (n=315) groups. An...
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