Article
Cost minimization of HLA-B*1502 screening before prescribing carbamazepine in Thailand.
International journal of clinical pharmacy - 1 Aug 2013
Tiamkao Somsak, Jitpimolmard Jukrapope, Sawanyawisuth Kittisak, Jitpimolmard Suthipun
Abstract excerpt
BACKGROUND: Carbamazepine (CBZ) is broadly used for the treatment of epilepsy, neuropathic pain and other neurological diseases, owing to its effectiveness and low price. CBZ can induce Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). There are several studies that found an association between HLA-B*1502 and CBZ-induced SJS/TEN, especially in people of Thai origin. In Thailand the prevalence...
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