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Article

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene.

PloS one - 1 Jan 2011

Pazirandeh Ahmad, Sultana Taranum, Mirza Momina, Rozell Björn, Hultenby Kjell, Wallis Karin, Vennström Björn, Davis Ben, Arner Anders, Heuchel Rainer, Löhr Matthias, Philipson Lennart, Sollerbrant Kerstin

Abstract excerpt

To determine the normal function of the Coxsackievirus and Adenovirus Receptor (CAR), a protein found in tight junctions and other intercellular complexes, we constructed a mouse line in which the CAR gene could be disrupted at any chosen time point in a broad spectrum of cell types and tissues. All knockouts examined displayed a dilated intestinal tract and atrophy of the exocrine pancreas with appearance of...

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Identifiers

PMID: 21674029
DOI: 10.1371/journal.pone.0020203
PMCID: PMC3108585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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