Article
Lack of compartmentalization of HIV-1 quasispecies between the gut and peripheral blood compartments.
The Journal of infectious diseases - 15 Jul 2011
Imamichi Hiromi, Degray Gerald, Dewar Robin L, Mannon Peter, Yao Michael, Chairez Cheryl, Sereti Irini, Kovacs Joseph A
Abstract excerpt
Compartmental differences in human immunodeficiency virus type 1 (HIV-1) between the gut and peripheral blood and within the gut were examined. Biopsy specimens from the colon and ileum and peripheral blood samples were collected from chronically HIV-1-infected individuals. HIV-1 envelope sequences were examined from cell-associated DNA and RNA and virion RNA. Phylogenetic analysis revealed no evidence of...
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