Article
Donor and recipient HLA/KIR genotypes do not predict liver transplantation outcome.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Sept 2011
Moroso Viviana, van der Meer Arnold, Tilanus Hugo W, Kazemier Geert, van der Laan Luc J W, Metselaar Herold J, Joosten Irma, Kwekkeboom Jaap
Abstract excerpt
Whether or not Natural Killer (NK) cells affect the immune response to solid organ allografts is still controversial. Main determinants of NK-cell activation are specific HLA/killer-cell immunoglobulin-like receptors (KIR) interactions that, in transplantation, may induce NK-cell alloreactivity. So far, in liver transplantation (LTX) donor-versus-recipient alloreactivity has not been investigated; in addition,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
