Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial colorectal cancer: eleven years of data from a registry program in Switzerland.

Familial cancer - 1 Sept 2011

Kovac Michal, Laczko Endre, Haider Ritva, Jiricny Josef, Mueller Hansjakob, Heinimann Karl, Marra Giancarlo

Abstract excerpt

Deleterious germ-line variants involving the DNA mismatch repair (MMR) genes have been identified as the cause of the hereditary nonpolyposis colorectal cancer syndrome known as the Lynch syndrome, but in numerous familial clusters of colon cancer, the cause remains obscure. We analyzed data for 235 German-speaking Swiss families with nonpolyposis forms of colorectal cancer (one of the largest and most ethnically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms, Hereditary Nonpolyposis
Share to DNA Mismatch Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Follow-Up Studies

Share to Germ-Line Mutation

Share to Neoplasm Proteins

Share to Registries

Share to Switzerland

Source

Identifiers

PMID: 21671081
DOI: 10.1007/s10689-011-9458-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial colorectal cancer: eleven years of data from a registry program in Switzerland.PMID 21671081Read ↗

Updates in the field of hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

Frequency of extracolonic tumors in Brazilian families with Lynch syndrome: analysis of a hereditary colorectal cancer institutional registry.Semantic proximity Read ↗

Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer.Semantic proximity Read ↗

Merged testing for colorectal cancer syndromes and re-evaluation of genetic variants improve diagnostic yield: Results from a nationwide prospective cohort.Semantic proximity Read ↗

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study.Semantic proximity Read ↗

Molecular Analysis of Colorectal Cancer Tumors from Patients with Mismatch Repair–Proficient Hereditary Nonpolyposis Colorectal Cancer Suggests Novel Carcinogenic PathwaysSemantic proximity Read ↗

Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome.Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome.Semantic proximity Read ↗

[Molecular pathology in hereditary colorectal cancer. Recommendations of the Collaborative German Study Group on hereditary colorectal cancer funded by the German Cancer Aid (Deutsche Krebshilfe)].Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer: review of clinical, molecular genetics, and counseling aspects.Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer (Lynch Syndrome) in Argentina: report from a referral hospital register.Semantic proximity Read ↗

Broadening Risk Profile in Familial Colorectal Cancer Type X; increased risk for five cancer types in the national Danish cohortSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.