Activity of KB-5246 against outer membrane mutants of Escherichia coli and Salmonella typhimurium.

doi:10.1128/AAC.34.7.1323

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Article

Activity of KB-5246 against outer membrane mutants of Escherichia coli and Salmonella typhimurium.

Antimicrobial agents and chemotherapy - 1 Jul 1990

Kotera Y, Inoue M, Mitsuhashi S

Abstract excerpt

The inhibitory activity of KB-5246 against Escherichia coli DNA gyrase and the antibacterial activity and apparent uptake in E. coli and Salmonella typhimurium outer membrane mutants of KB-5246 were measured. The 50% inhibitory concentrations of KB-5246, ciprofloxacin, oflaxacin, and norfloxacin...

Topics

4-Quinolones
Anti-Infective Agents
Bacterial Outer Membrane Proteins
Chemical Phenomena
Chemistry, Physical
Culture Media
Escherichia coli
Fluoroquinolones
Indicators and Reagents
Microbial Sensitivity Tests
Mutation
Phenalenes
Quinolones
Salmonella typhimurium
Topoisomerase II Inhibitors

Source

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Identifiers

PMID: 2167038
DOI: 10.1128/AAC.34.7.1323
PMCID: PMC175974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2167038-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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