Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes.

The American journal of pathology - 1 Aug 1990

Hsu S M, Xie S S, Hsu P L

Abstract excerpt

Two Hodgkin's Reed-Sternberg cell (H-RS) lines, HDLM-1 and KM-H2, have phenotypes and functional properties very similar to those of H-RS cells in tissues. These two types of cells were induced to differentiate with a combination of phorbol ester, retinoic acid, and extracellular matrix. The induced cells displayed the morphology of histiocytes or histiocytelike cells, with a small, round or oval, eccentric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to Antigens, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Cytokines

Share to Extracellular Matrix

Share to Gene Rearrangement

Share to Lymphocytes

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 2167011
PMCID: PMC1877620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes.PMID 2167011Read ↗

Generation of Cells With Hodgkin’s and Reed-Sternberg Phenotype Through Downregulation of CD99 (Mic2)Semantic proximity Read ↗

The nature of Reed-Sternberg cells: phenotype, genotype, and other properties.Semantic proximity Read ↗

Recent Results on the Biology of Hodgkin and Reed-Sternberg cells: II. Continuous Cell LinesSemantic proximity Read ↗

Lymphomas of true histiocytic origin. Expression of different phenotypes in so-called true histiocytic lymphoma and malignant histiocytosis.Semantic proximity Read ↗

Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions - a perspective in vitro model for drug testing.Semantic proximity Read ↗

Phenotypic analysis of an established cell line derived from a patient with Hodgkin's disease (HD).Semantic proximity Read ↗

Is the Hodgkin cell a T- or B-lymphocyte? Recent evidence from geno- and immunophenotypic analysis and in-vitro cell lines.Semantic proximity Read ↗

Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy material.Semantic proximity Read ↗

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cellsSemantic proximity Read ↗

DOR-1, A novel CD10+ stromal cell line derived from progressive Langerhans cell histiocytosis of bone.Semantic proximity Read ↗

Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95.Semantic proximity Read ↗

Establishment of a Langerhans cell histiocytosis lesion cell line with dermal dendritic cell characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.