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Article

ASIC1a polymorphism is associated with temporal lobe epilepsy.

Epilepsy research - 1 Sept 2011

Lv Rui-Juan, He Jin-Sheng, Fu Yuan-Hui, Zhang Ya-Qing, Shao Xiao-Qiu, Wu Li-Wen, Lu Qiang, Jin Li-Ri, Liu Hui

Abstract excerpt

Recent in vitro and in vivo data show that acid-sensing ion channel 1a (ASIC1a) activation enhances neuronal excitability in the hippocampus and neocortex, indicating that ASIC1a might play a role in the generation and maintenance of epileptic seizures. The aim of this study was to investigate association of the ASIC1a gene with temporal lobe epilepsy (TLE) for the first time. Six tag single-nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21664108
DOI: 10.1016/j.eplepsyres.2011.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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