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Article

Coupling single base extension to a spectral codification tool for increased throughput screening.

Journal of biotechnology - 20 Jul 2011

Giestas Letícia, Lima João Carlos, Baptista Pedro V

Abstract excerpt

We report a new strategy that combines a Förster Resonance Energy Transfer (FRET) based spectral codification tool with a single base extension (SBE) reaction for rapid and medium-throughput analysis of single nucleotide polymorphisms (SNPs). This strategy is based on the spectral codification - a donor (fluorophore labeled probe complementary to the region adjacent to an SNP) is used to induce specific FRET...

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PMID: 21663776
DOI: 10.1016/j.jbiotec.2011.05.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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