Article
Fluorescent DNA base modifications and substitutes: multiple fluorophore labeling and the DETEQ concept.
Annals of the New York Academy of Sciences - 1 Jan 2008
Wagenknecht Hans-Achim
Abstract excerpt
There is an increasing need for fluorescent nucleic acid probes that are able to sense genetic variations without the application of enzymes. The incorporation of organic fluorophores either as DNA base modifications or as DNA base substitutions represents a powerful and versatile method for such new fluorescent DNA assays. Multiple labeling of oligonucleotides using several adjacent chromophore-modified DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
