Article
Association of TCF4 gene polymorphisms with Fuchs' corneal dystrophy in the Chinese.
Investigative ophthalmology & visual science - 29 Jul 2011
Thalamuthu Anbupalam, Khor Chiea Chuen, Venkataraman Divya, Koh Li Wei, Tan Donald T H, Aung Tin, Mehta Jodhbir S, Vithana Eranga N
Abstract excerpt
PURPOSE: To test the association between TCF4, a gene recently found to confer susceptibility to Fuchs' corneal dystrophy (FCD) in Caucasian populations, and Chinese patients with FCD. METHODS: Fifty-seven Chinese subjects with clinically diagnosed FCD and 121 normal control subjects were recruited. Genomic DNA was extracted and the 18 single nucleotide polymorphisms (SNPs) within TCF4 were genotyped (Sequenom...
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