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Article

Transethnic replication of association of CTG18.1 repeat expansion of TCF4 gene with Fuchs' corneal dystrophy in Chinese implies common causal variant.

Investigative ophthalmology & visual science - 8 Oct 2014

Xing Chao, Gong Xin, Hussain Imran, Khor Chiea-Chuen, Tan Donald T H, Aung Tin, Mehta Jodhbir S, Vithana Eranga N, Mootha V Vinod

Abstract excerpt

PURPOSE: To test the association between the CTG18.1 trinucleotide repeat expansion of TCF4 gene and Fuchs' endothelial corneal dystrophy (FECD) in a Chinese population. METHODS: The trinucleotide repeat polymorphism CTG18.1 was genotyped using short tandem repeat and triplet repeat primed polymerase chain reaction assays in 57 Chinese subjects with FECD and 121 controls. Statistical association of the expanded...

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Source

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Identifiers

PMID: 25298419
DOI: 10.1167/iovs.14-15390
PMCID: PMC4224583

Genes

TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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