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Article

Association of polymorphisms in the intron of TCF4 gene to late-onset Fuchs endothelial corneal dystrophy: An Indian cohort study.

Indian journal of ophthalmology - 1 Oct 2017

Rao Bhavna S, Tharigopala Arokiasamy, Rachapalli Sudhir R, Rajagopal Rama, Soumittra Nagasamy

Abstract excerpt

PURPOSE: Fuchs endothelial corneal dystrophy (FECD) is a progressive degenerative disease of the corneal endothelium. It is genetically heterogeneous and follows either an autosomal dominant or sporadic pattern of inheritance. Here, we have explored the association of four previously reported intronic single nucleotide polymorphisms and intronic CTG repeat expansions in TCF4 gene to FECD in an Indian cohort....

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Share to Endothelium, Corneal
Share to Fuchs' Endothelial Dystrophy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29044056
DOI: 10.4103/ijo.IJO_191_17
PMCID: PMC5678327

Genes

TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of polymorphisms in the intron of TCF4 gene to late-onset Fuchs endothelial corneal dystrophy: An Indian cohort study.PMID 29044056Read ↗

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