Article
Association of transcription factor 4 (TCF4) and protein tyrosine phosphatase, receptor type G (PTPRG) with corneal dystrophies in southern Chinese.
Ophthalmic genetics - 1 Sept 2014
Wang Kai Jie, Jhanji Vishal, Chen Jianhuan, Law Ricky Wai-Kei, Leung Alfred Tai-Shing, Zhang Mingzhi, Wang Ningli, Pang Chi-Pui, Yam Gary Hin-Fai
Abstract excerpt
Fuchs' endothelial dystrophy is a common type of posterior CD characterized by the development of gutta in the Descemet membrane. Recently, TCF4 was considered as a major risk gene for European FED cases. However, another recent report has shown that rs613872 was not associated with Singaporean Chinese FEDs. Recent reports indicate the genotypic heterogeneity of FEDs in different ethnic populations. It is thus...
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