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Article

Do complement factor H 402Y and C7 M allotypes predispose to (typical) haemolytic uraemic syndrome?

International journal of immunogenetics - 1 Oct 2011

Poolpol K, Gadner B, Neururer S, Mellmann A, Karch H, Orth D, Würzner R

Abstract excerpt

Typical haemolytic uraemic syndrome (HUS) is mainly caused by infections with enterohaemorrhagic Escherichia coli, whereas in atypical, nonbacteria-associated HUS, complement plays a dominant role. Recently, complement has also been shown to be involved in typical HUS. In this study, mostly weakly significant associations with homozygosities of complement allotype C7 M and inversely with factor H 402H were found,...

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Identifiers

PMID: 21649859
DOI: 10.1111/j.1744-313X.2011.01017.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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