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Article

Complement factor H and hemolytic uremic syndrome.

International immunopharmacology - 1 Mar 2001

Zipfel P F, Skerka C, Caprioli J, Manuelian T, Neumann H H, Noris M, Remuzzi G

Abstract excerpt

Factor H is a 150 kDa single chain plasma glycoprotein that plays a pivotal role in the regulation of the alternative pathway of complement. Primary sequence analysis reveals a structural organization of this plasma protein, in 20 homologous units, called Short Consensus Repeats (SCRs), each about 60 amino acids long. Biochemical and genetic studies show an association between factor H deficiency and human...

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Identifiers

PMID: 11367530
DOI: 10.1016/s1567-5769(00)00047-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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