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Article

IDH1 and IDH2 mutations in pediatric acute leukemia.

Leukemia - 1 Oct 2011

Andersson A K, Miller D W, Lynch J A, Lemoff A S, Cai Z, Pounds S B, Radtke I, Yan B, Schuetz J D, Rubnitz J E, Ribeiro R C, Raimondi S C, Zhang J, Mullighan C G, Shurtleff S A, Schulman B A, Downing J R

Abstract excerpt

To investigate the frequency of isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) mutations in pediatric acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL), we sequenced these genes in diagnostic samples from 515 patients (227 AMLs and 288 ALLs). Somatic IDH1/IDH2 mutations were rare in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21647154
DOI: 10.1038/leu.2011.133
PMCID: PMC3883450

Genes

IDH2
IDH1
FLT3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21647154-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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