Article
Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population.
Molecular biology reports - 1 Feb 2012
Ignatovica Vita, Latkovskis Gustavs, Peculis Raitis, Megnis Kaspars, Schioth Helgi B, Vaivade Iveta, Fridmanis Davids, Pirags Valdis, Erglis Andrejs, Klovins Janis
Abstract excerpt
The purinergic 1 receptor (P2RY1) has been implicated in development of heart disease and in individual pharmacodynamic response to anticoagulant therapies. However, the association of polymorphisms in the P2RY1 gene with myocardial infarction (MI), and its associated conditions, has yet to be reported in the literature. We evaluated seven known SNPs in P2RY1 for association with MI in a Latvian population. Seven...
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