Article
Association of the purinergic receptor P2Y, G-protein coupled, 2 (P2RY2) gene with myocardial infarction in Japanese men.
Circulation journal : official journal of the Japanese Circulation Society - 1 Dec 2009
Wang Zhao Xia, Nakayama Tomohiro, Sato Naoyuki, Izumi Yoichi, Kasamaki Yuji, Ohta Masakatsu, Soma Masayoshi, Aoi Noriko, Matsumoto Koichi, Ozawa Yukio, Ma Yi Tong, Doba Nobutaka, Hinohara Shigeaki
Abstract excerpt
BACKGROUND: Atherosclerosis leads to myocardial infarction (MI) and P2RY2 plays an important role in this process. The aim of the present study was to investigate the association between human P2RY2 and MI via a haplotype-based case-control study that additionally analyzed the group by sex. METHODS AND RESULTS: The 310 MI patients and 254 controls were genotyped for 5 single-nucleotide polymorphisms (SNPs) of the...
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