Article
Are transposons a cause of ageing?
Mutation research - 1 Mar 1990
Murray V
Abstract excerpt
A hypothesis for ageing is proposed based on the properties of transposons. During the process of transposition, one copy of the DNA sequence generally remains at the same position while the other copy moves to another location in the genome. In this manner the DNA sequence of the transposon is effectively duplicated. With time the number of transposons increases exponentially and since in their new location they...
Topics
- Aging
- Animals
- DNA Transposable Elements
- Gene Expression Regulation
- Humans
- Models, Theoretical
- Multigene Family
- Mutation