Article
Yeast cAMP-dependent protein kinase regulatory subunit mutations display a variety of phenotypes.
The Journal of biological chemistry - 15 Jul 1990
Cannon J F, Gitan R, Tatchell K
Abstract excerpt
Ten spontaneous and four in vitro constructed mutations in the gene encoding the regulatory subunit of cAMP-dependent protein kinase of Saccharomyces cerevisiae display very different phenotypes. The DNA nucleotide sequence of each spontaneous mutation was determined. Mutations were found in both the cAMP-binding domains and proximal to the cAMP-dependent protein kinase phosphorylation site. The latter mutations...
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