Article
Genotoxic effects of doxorubicin in cultured human lymphocytes with different glutathione S-transferase genotypes.
Mutation research - 18 Sept 2011
Ramos D L, Gaspar J F, Pingarilho M, Gil O M, Fernandes A S, Rueff J, Oliveira N G
Abstract excerpt
Doxorubicin (Dox) is a widely used drug in oncology with a broad spectrum of interactions with various cellular components; therefore, it is likely to act through different mechanisms. In clinical practice there is inter-individual variability in cytotoxic drug response and in the occurrence of a...
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