Article
Improved homo L-lactic acid fermentation from xylose by abolishment of the phosphoketolase pathway and enhancement of the pentose phosphate pathway in genetically modified xylose-assimilating Lactococcus lactis.
Applied microbiology and biotechnology - 1 Sept 2011
Shinkawa Satoru, Okano Kenji, Yoshida Shogo, Tanaka Tsutomu, Ogino Chiaki, Fukuda Hideki, Kondo Akihiko
Abstract excerpt
In order to achieve efficient homo L-lactic acid fermentation from xylose, we first carried out addition of xylose assimilation ability to Lactococcus lactis IL 1403 by introducing a plasmid carrying the xylRAB genes from L. lactis IO-1 (pXylRAB). Then modification of xylose assimilation pathway was carried out. L. lactis has two pathways for xylose assimilation called the phosphoketolase pathway (PK pathway)...
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