Article
Repeat motif-containing regions within thyroglobulin.
The Journal of biological chemistry - 29 Jul 2011
Lee Jaemin, Arvan Peter
Abstract excerpt
Thyroglobulin (precursor for thyroid hormone synthesis) is a large secreted glycoprotein comprising contiguous region I (multiple type-1 repeating units engaging the first ∼1,191 residues, followed by a ∼245-residue hinge region), regions II-III (multiple type-2 and 3 repeating units, comprising ∼720 residues), and the C-terminal cholinesterase-like (ChEL) domain (∼570 residues). A signal peptide attached to ChEL...
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