Article
Genetic variability of the coding region for the prion protein gene (PRNP) in gayal (Bos frontalis).
Molecular biology reports - 1 Feb 2012
Xi Dongmei, Liu Qing, Guo Jianhong, Yu Hongman, Yang Yuai, He Yiduo, Mao Huaming, Gou Xiao, Deng Weidong
Abstract excerpt
The gayal (Bos frontalis) is a rare semi-wild bovid species in which bovine spongiform encephalopathy (BSE) has not been reported. Polymorphisms of the prion protein gene (PRNP) have been correlated significantly with resistance to BSE. In this study, the coding region of PRNP was cloned and characterized in samples from 125 gayal. A total of ten single nucleotide polymorphisms (SNPs), including six silent...
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