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Article

Genetic risk factors for type 2 diabetes mellitus and response to sulfonylurea treatment.

Pharmacogenetics and genomics - 1 Aug 2011

Swen Jesse J, Guchelaar Henk-Jan, Baak-Pablo Renée F, Assendelft Willem J J, Wessels Judith A M

Abstract excerpt

OBJECTIVE: After the identification of type 2 diabetes mellitus (T2DM) risk alleles from genome-wide association studies, models have been developed to identify subjects at high risk to develop T2DM. We hypothesize that a panel of 20 repeatedly associated T2DM risk alleles influences response to sulfonylureas (SUs). METHODS: Two hundred and seven incident SU (tolbutamide, glibenclamide, glimepiride, gliclazide)...

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Identifiers

PMID: 21633322
DOI: 10.1097/FPC.0b013e3283478173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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