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Article

Positive Effects of Combined Antiretroviral Therapy on CD4 <sup>+</sup> T Cell Homeostasis and Function in Advanced HIV Disease

4 Jul 1997

Abstract excerpt

Highly active antiretroviral therapy (HAART) increases CD4(+) cell numbers, but its ability to correct the human immunodeficiency virus (HIV)-induced immune deficiency remains unknown. A three-phase T cell reconstitution was demonstrated after HAART, with: (i) an early rise of memory CD4(+) cells, (ii) a reduction in T cell activation correlated to the decreasing retroviral activity together with an improved...

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PMID: 9204894
DOI: 10.1126/science.277.5322.112

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