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Article

Genetic variation of adenylation domains of the anabaenopeptin synthesis operon and evolution of substrate promiscuity.

Journal of bacteriology - 1 Aug 2011

Christiansen Guntram, Philmus Benjamin, Hemscheidt Thomas, Kurmayer Rainer

Abstract excerpt

Anabaenopeptins (AP) are bioactive cyclic hexapeptides synthesized nonribosomally in cyanobacteria. APs are characterized by several conserved motifs, including the ureido bond, N-methylation in position 5, and d-Lys in position 2. All other positions of the AP molecule are variable, resulting in numerous structural variants. We have identified a nonribosomal peptide synthetase (NRPS) operon from Planktothrix...

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Identifiers

PMID: 21622740
DOI: 10.1128/JB.00360-11
PMCID: PMC3147517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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