Article
Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases.
Fungal genetics and biology : FG & B - 1 Mar 2018
Brandenburger Eileen, Braga Daniel, Kombrink Anja, Lackner Gerald, Gressler Julia, Künzler Markus, Hoffmeister Dirk
Abstract excerpt
Among the invaluable benefits of basidiomycete genomics is the dramatically enhanced insight into the potential capacity to biosynthesize natural products. This study focuses on adenylate-forming reductases, which is a group of natural product biosynthesis enzymes that resembles non-ribosomal peptide synthetases, yet serves to modify one substrate, rather than to condense two or more building blocks....
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