Article
Genetic identification of microcystin ecotypes in toxic cyanobacteria of the genus Planktothrix.
Microbiology (Reading, England) - 1 May 2005
Kurmayer Rainer, Christiansen Guntram, Gumpenberger Marlies, Fastner Jutta
Abstract excerpt
Microcystins (MCs) are toxic heptapeptides which are synthesized by the filamentous cyanobacterium Planktothrix and other genera via non-ribosomal peptide synthesis. MCs share the common structure cyclo(-D-ala1-L-X2-D-erythro-beta-iso-aspartic acid3-L-Z4-adda5-D-Glu6-N-methyl-dehydroalanine7) [Adda; (2S, 3S, 8S, 9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid], in which numerous MC variants...
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