Article
Epstein-Barr virus genotypes associated with nasopharyngeal carcinoma in southern China.
Virology - 1 Jul 1990
Lung M L, Chang R S, Huang M L, Guo H Y, Choy D, Sham J, Tsao S Y, Cheng P, Ng M H
Abstract excerpt
We have used probes representing approximately two-thirds of the Epstein-Barr virus (EBV) genome to examine genetic polymorphism of wild-type EBV directly detected in 28 nasopharyngeal carcinoma (NPC) tissues from Southern China. In the hypervariable regions containing reiterated sequences, this analysis showed that while naturally occurring viruses are genetically diverse, only one genotype was detectable in...
Topics
- Biopsy
- Blotting, Southern
- Cell Line
- China
- DNA, Viral
- Deoxyribonuclease BamHI
- Genetic Variation
- Genotype
- Herpesvirus 4, Human
- Humans
- Nasopharyngeal Neoplasms
