Genetic background of multiple sclerosis.

doi:10.1016/j.autrev.2011.05.007

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Article

Genetic background of multiple sclerosis.

Autoimmunity reviews - 1 Jan 2012

Sadovnick A Dessa

Abstract excerpt

Multiple sclerosis (MS) is a one of the group of diseases labeled as "common complex". Virtually all common complex traits, genetic and environmental components have important roles, both independently and interactively, in disease susceptibility and stochastic and epigenetic effects cannot be overlooked. Data presented are largely part of the Canada-wide prospective, population-based longitudinal Canadian...

Topics

Canada
Epistasis, Genetic
Epstein-Barr Virus Infections
Genetic Predisposition to Disease
Genome-Wide Association Study
HLA-DRB1 Chains
Herpesvirus 4, Human
Humans
Major Histocompatibility Complex
Multifactorial Inheritance
Multiple Sclerosis
Polymorphism, Genetic
Risk
Sex Factors
Vitamin D

Source

Open in PubMed

Identifiers

PMID: 21619948
DOI: 10.1016/j.autrev.2011.05.007

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