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Article

A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma.

BMC cancer - 29 May 2011

Mirabello Lisa, Yu Kai, Berndt Sonja I, Burdett Laurie, Wang Zhaoming, Chowdhury Salma, Teshome Kedest, Uzoka Arinze, Hutchinson Amy, Grotmol Tom, Douglass Chester, Hayes Richard B, Hoover Robert N, Savage Sharon A

Abstract excerpt

BACKGROUND: Osteosarcoma (OS) is a bone malignancy which occurs primarily in adolescents. Since it occurs during a period of rapid growth, genes important in bone formation and growth are plausible modifiers of risk. Genes involved in DNA repair and ribosomal function may contribute to OS pathogenesis, because they maintain the integrity of critical cellular processes. We evaluated these hypotheses in an OS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21619704
DOI: 10.1186/1471-2407-11-209
PMCID: PMC3138419

Genes

FANCM
FGF2
FGFR3
GNRH2
IGF1
MDM2
MPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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