Article
Virological breakthrough and resistance in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice.
Hepatology (Baltimore, Md.) - 1 Jun 2011
Hongthanakorn Chanunta, Chotiyaputta Watcharasak, Oberhelman Kelly, Fontana Robert J, Marrero Jorge A, Licari Tracy, Lok Anna S F
Abstract excerpt
UNLABELLED: Virological breakthrough (VBT) is the first manifestation of antiviral drug resistance during nucleos(t)ide analogue (NUC) treatment of chronic hepatitis B (CHB), but not all VBTs are due to drug resistance. This study sought to determine the incidence of VBT and genotypic resistance (GR) in patients with CHB who were receiving NUCs in clinical practice. Records of patients with CHB who were receiving...
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